Probiotics Aspergillus oryzae and Lactobacillus sakei reduce IgE and increase Th1 cytokines in an ovalbumin-induced murine model of allergy
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چکیده
Probiotic bacteria exert beneficial effects on human health through suppression of harmful microorganisms and immunomodulatory activity. Preclinical and clinical studies have accumulated evidence of the effect of orally administered probiotics in the management of allergic diseases, diabetes, obesity, heart disease, and other debilitating disorders. For example, oral administration of Bifidobacterium lactis modulates immune parameters and mitigates allergic symptoms. Other probiotic bacteria exhibited cholesterol-lowering effects by interacting with bile acids, and could decrease lipid concentration in serum improving hemorheology. The administration of probiotics to infants altered the composition of their Int J Anal Bio-Sci Vol. 3, No 4 (2015)
منابع مشابه
Immunomodulatory and anti-allergic effects of orally administered Lactobacillus species in ovalbumin-sensitized mice.
We investigated the effects of orally administered probiotic bacteria (Lactobacillus species) as allergic immune modulators in ovalbumin (OVA)-sensitized mice. BALB/c mice were intraperitoneally injected with OVA twice at a 2-week interval for allergy sensitization. The mice were then orally administered Lactobacillus casei YIT9029 (L1), L. casei HY7201 (L2), L. brevis HY7401 (L3), or L. planta...
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